January 1, 1998Journal of Cardiovascular Pharmacology
Present and Future Role of Combination Treatment in Hypertension
Population
Hypertensive patients
Design
Review
Authors
Discussion
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Member takes
Implication
May support fixed-dose combinations to improve adherence in hypertension; leaves open need for outcome trials.
Structured PICO
P
Population
Hypertensive patients
I
Intervention
Combination treatment with two antihypertensive drugs (including fixed combinations)
Combination antihypertensive therapy, particularly fixed-dose combinations, simplifies treatment regimens and may improve poor patient compliance.
Cite This Study
Mancia et al. (1998) studied this question.