Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 1970Experimental Biology and Medicine

Antigenic Variation of Rhinovirus Type 22

View Full Paper
Ask AI
Bookmark
Share

Population

18 type 22 rhinoviruses isolated in the laboratory

Comparison

Immune serum prepared to variant virus (Chase) vs Immune serum to the prototype strain (127-CV22)

Design

Preclinical

Authors

JSJ. H. SchiebleCalifornia Health and Human Services AgencyHLH. Edwin LennetteUnited States Department of StateVFVictor L. FoxBrigham and Women's Hospital

Discussion

Loading...

Member takes

Implication

May guide rhinovirus antigenic assays; leaves open human vaccine relevance.

Structured PICO

P
Population
18 type 22 rhinoviruses isolated in the laboratory
I
Intervention
Immune serum prepared to variant virus (Chase)
C
Comparator
Immune serum to the prototype strain (127-CV22)
O
Outcome
Neutralization of virus strainssurrogate

The Chase virus represents a 'prime strain' of rhinovirus type 22, as its immune serum can neutralize both prototype and variant strains.

Cite This Study

Schieble et al. (1970) studied this question.

synapsesocial.com/papers/6a710e108031ec7bb1dcbcc9https://doi.org/10.3181/00379727-133-34468
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rhinoviruses: An Antigenic Study of the Prototype Virus Strains1974 · 14 citations
  2. 2Hyper-antigenic variation occurs with human rhinovirus type 171997 · 9 citations
  3. 3Additional Rhinovirus Serotypes1964 · 23 citations
  4. 4Isolation of Rhinovirus Intertypes Related to Either Rhinoviruses 12 and 78 or 36 and 581983 · 9 citations
  5. 5Antibody to Rhinovirus in Human Sera. I. Standardization of a Neutralization Test1968 · 28 citations