Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 1, 2016BMJ Open Diabetes Research & CareOpen Access

Peripheral sensory neuropathy is associated with altered postocclusive reactive hyperemia in the diabetic foot

View Full Paper
Ask AI
Bookmark
Share

Population

99 participants with type 2 diabetes

Design

Cross-sectional

Authors

ABAlex BarwickSouthern Cross UniversityJTJohn TessierUniversity of Newcastle AustraliaXJXanne Janse de JongeGriffith University

Discussion

Loading...

Member takes

Implication

Peripheral sensory neuropathy was associated with impaired foot microvascular reactivity in T2D; this cross-sectional link leaves causal and clinical implications open.

Structured PICO

P
Population
99 participants with type 2 diabetes
O
Outcome
Postocclusive reactive hyperemia (peak perfusion following occlusion and time to reach this peak) measured with laser Doppler in the halluxsurrogate

Peripheral sensory neuropathy in type 2 diabetes is associated with delayed microvascular reactivity in the lower limb, suggesting a link between neuropathy and microvascular dysfunction.

Cite This Study

Barwick et al. (2016) studied this question.

synapsesocial.com/papers/6a710e692163a0a01bc53d59https://doi.org/10.1136/bmjdrc-2016-000235
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tool Chest2007 · 19 citations
  2. 2Albumin Excretion Rate and Cardiovascular Risk2005 · 40 citations
  3. 3Relationship between post‐occlusive forearm skin reactive hyperaemia and vascular disease in patients with Type 2 diabetes—a novel index for detecting micro‐ and macrovascular dysfunction using laser Doppler flowmetry2009 · 91 citations
  4. 4Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration.1998 · 352 citations
  5. 5Statins enhance postischemic hyperemia in the skin circulation of hypercholesterolemic patients2003 · 176 citations