Why the study?
Are myogenic microvascular responses impaired in patients with long-duration Type 1 diabetes compared to controls?
Population
75 subjects: 20 control subjects and 55 long-duration Type 1 diabetic patients.
Comparison
Measurement of hyperaemic response on the dorsum… vs Control subjects without diabetes
Design
Cross-sectional
Authors
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May indicate microvascular impairment in long-duration T1D; hypothesis-generating for neuropathy-linked rigidity, longitudinal studies needed.
Are myogenic microvascular responses impaired in patients with long-duration Type 1 diabetes compared to controls?
Long-duration Type 1 diabetes impairs the myogenic peak post-ischaemic hyperaemic response, while neuropathic patients exhibit rapid vasodilatation likely reflecting increased arterial rigidity.
Walmsley et al. (1990) studied this question.
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