Why the study?
Does spontaneous diabetes alter cardiac function and biochemistry in isolated perfused hearts from BB rats?
Does spontaneous diabetes alter cardiac function and biochemistry in isolated perfused hearts from BB rats?
Spontaneous diabetes in BB rats produces cardiac dysfunction similar to chemical diabetes models and human diabetes mellitus.
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Supports BB rat model for diabetic cardiomyopathy research; extends chemical diabetes findings but leaves clinical translation open.
Rodrigues et al. (1990) studied this question.
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