Why the study?
Identifying adherence to direct oral anticoagulants plays a major role in treatment efficacy and safety.
Does the DOAC Dipstick test accurately detect direct oral factor Xa inhibitors in urine compared to plasma chromogenic assays in outpatients?
Population
120 outpatients taking DOACs (77 on rivaroxaban, 43 on apixaban)
Comparison
DOAC Dipstick urine test vs chromogenic substrate assays on plasma samples
Design
Prospective observational consecutive cohort study
Authors
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DOAC Dipstick may support outpatient adherence checks; leaves open need for randomized validation before routine use.
Does the DOAC Dipstick test accurately detect direct oral factor Xa inhibitors in urine compared to plasma chromogenic assays in outpatients?
The DOAC Dipstick test is a highly sensitive tool for detecting direct oral factor Xa inhibitors in urine samples, offering a practical method to assess medication adherence in outpatients.
Papageorgiou et al. (2023) studied this question.
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