Population
1996 men and women between the ages of 40 and 64 years from the Japanese general population
Design
Cohort
Follow-up
18 years
Authors
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BP ≥140/90 mmHg associated with higher CVD mortality in Japanese adults; extends observational data but leaves treatment thresholds open pending RCTs.
Cardiovascular mortality increases significantly at blood pressures ≥140/90 mmHg in the Japanese population, supporting treatment initiation at or below this threshold.
Takagi et al. (2000) studied this question.
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