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March 1, 1964American Journal of Physiology-Legacy Content

Effects of atrial and ventricular tachycardias on the cardiovascular dynamics

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Why the study?

How do atrial and ventricular tachycardias affect cardiovascular dynamics in anesthetized dogs?

Population

Anesthetized dogs

Comparison

Induced atrial and ventricular tachycardias vs Baseline state or atrial vs. ventricular…

Design

Preclinical

Authors

JNJiro NakanoKansai Medical University

Discussion

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Implication

VT impairs hemodynamics more than AT at matched rates in dogs; leaves open human translation and differential rate targets.

Structured PICO

How do atrial and ventricular tachycardias affect cardiovascular dynamics in anesthetized dogs?

P
Population
Anesthetized dogs
I
Intervention
Induced atrial and ventricular tachycardias
C
Comparator
Baseline state or atrial vs. ventricular tachycardia
O
Outcome
Cardiovascular dynamics (mean arterial pressure, stroke volume, cardiac output, regional arterial blood flows, ventricular function curves, myocardial contractile force, pulmonary arterial pressure, left and right atrial pressures, and total pulmonary and regional peripheral resistances)surrogate

This preclinical study demonstrates that both atrial and ventricular tachycardias impair cardiovascular hemodynamics, with ventricular tachycardia producing more severe derangements at equivalent rates.

Cite This Study

Jiro Nakano (1964) studied this question.

synapsesocial.com/papers/6a71547235aa2c282ce2a2f6https://doi.org/10.1152/ajplegacy.1964.206.3.547

Topics

Ventricular arrhythmias
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hemodynamic Effects of Experimentally Induced Atrial and Ventricular Tachycardia1966 · 2 citations
  2. 2Effect of Heart Rate on Coronary Circulation1966 · 2 citations
  3. 3Effect of Atrial and Ventricular Tachycardia on Cardiac Oxygen Consumption1965 · 18 citations
  4. 4Hemodynamic Responses to Rapid Pacing: A Model for Tachycardia Differentiation1988 · 25 citations
  5. 5Effects of Tachycardia on Regional Wall Motion in Acute Ischemic Canine Heart2004