Why the study?
Does very low-dose infusion of atrial natriuretic hormone reduce plasma aldosterone in normal young men in a salt-depleted state?
Population
7 normal young men in a salt-depleted state
Comparison
Infusion of 0.47 pmol.kg-1.min-1 of human… vs Placebo infusion
Design
Other
Follow-up
2.5 hours
Authors
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Physiological ANH changes may suppress aldosterone; leaves open clinical relevance in patients with aldosterone dysregulation.
Does very low-dose infusion of atrial natriuretic hormone reduce plasma aldosterone in normal young men in a salt-depleted state?
Even small changes in atrial natriuretic hormone levels within the normal physiological range significantly suppress aldosterone production.
Yoram Shenker (1989) studied this question.
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