Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 20, 2017Journal of Hypertension

Impact of aortic rather than brachial pulsatile haemodynamics on variations in end-organ measures across the full adult blood pressure range

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Do aortic pulsatile hemodynamics better index end-organ effects compared to brachial blood pressure across the adult blood pressure range?

Population

1307 community participants, including normotensive (50.5%) and hypertensive adults

Comparison

Aortic pulsatile hemodynamics vs Brachial pulsatile hemodynamics

Design

Cohort

Authors

BHBryan HodsonGNGavin R. NortonIBImraan Ballim

Discussion

Loading...

Member takes

Overview

Aortic pulsatile measures may better index LVMI effects than brachial across BP range; leaves open whether targeting them alters outcomes.

Structured PICO

Do aortic pulsatile hemodynamics better index end-organ effects compared to brachial blood pressure across the adult blood pressure range?

P
Population
1307 community participants, including normotensive (50.5%) and hypertensive adults
I
Intervention
Aortic pulsatile hemodynamics (aortic backward wave pressure and aortic pulse wave velocity)
C
Comparator
Brachial pulsatile hemodynamics (brachial pulse pressure or systolic blood pressure)
O
Outcome
Variations in left ventricular mass index (LVMI), carotid intima-media thickness (IMT), and estimated glomerular filtration rate (eGFR)surrogate

Aortic pulsatile hemodynamics account for end-organ effects more consistently than steady-state pressures, particularly in the normotensive blood pressure range.

Cite This Study

Hodson et al. (2017) studied this question.

synapsesocial.com/papers/6a71554b35aa2c282ce2a45chttps://doi.org/10.1097/hjh.0000000000001471
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Aortic, but not brachial blood pressure category enhances the ability to identify target organ changes in normotensives2013 · 17 citations
  2. 2Indexes of Aortic Pressure Augmentation Markedly Underestimate the Contribution of Reflected Waves Toward Variations in Aortic Pressure and Left Ventricular Mass2014 · 52 citations
  3. 3Quantification of Wave Reflection in the Human Aorta From Pressure Alone2006 · 310 citations
  4. 4Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis2010 · 1,368 citations
  5. 5Effects of Intensive Blood Pressure Lowering on Cardiovascular and Renal Outcomes: A Systematic Review and Meta-Analysis2012 · 779 citations