A cloned partial cDNA copy of the coxsackievirus B3 genome can successfully detect various enteroviruses in infected cells using nucleic acid hybridization.
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Supports enterovirus hybridization assays in research; leaves open clinical diagnostic translation.
A cloned partial cDNA copy of the coxsackievirus B3 genome was used for detecting enteroviruses in infected cells by employing a nucleic acid hybridization procedure. Cells infected with coxsackieviruses A and B, echovirus, and poliovirus gave positive hybridization signals, whereas cells infected with nonrelated viruses did not.
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Hyypiä et al. (1984) studied this question.
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