Why the study?
Can in situ hybridization using a cloned cDNA probe detect coxsackievirus RNA in cardiac tissue from infected patients?
Population
Cardiac tissue samples from patients diagnosed with coxsackievirus infection and normal control cardiac…
Comparison
In situ hybridization using a cloned cDNA probe… vs Normal control cardiac samples
Design
Case-control
Authors
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Supports viral detection in myocarditis cases; hypothesis-generating for in situ hybridization, should not yet change practice.
Can in situ hybridization using a cloned cDNA probe detect coxsackievirus RNA in cardiac tissue from infected patients?
In situ hybridization can successfully detect enteroviral RNA in cardiac tissue of patients with suspected coxsackievirus infection, offering a potential diagnostic tool for viral myocarditis.
Easton et al. (1988) studied this question.
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