Why the study?
Previous studies on statins for preventing delirium yielded controversial results and did not sufficiently consider disease severity or statin properties.
Does statin use increase the occurrence of delirium in intensive care unit patients?
Does statin use increase the occurrence of delirium in intensive care unit patients?
Statin use in ICU patients with mild to moderate disease severity is associated with an increased risk of delirium, regardless of whether the statin is lipophilic or hydrophilic.
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Statin use was associated with higher delirium risk in milder ICU cases; leaves open causality and whether statins should be adjusted.
An et al. (2021) studied this question.
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