Key result
Barnidipine is a novel, long-acting calcium antagonist with once-daily dosing, good tolerability, and durable antihypertensive effects for the treatment of hypertension.
Barnidipine is a long-acting calcium channel blocker that provides effective once-daily blood pressure control with good tolerability.
Barnidipine may support once-daily BP control in hypertension; leaves open need for head-to-head RCTs versus established CCBs.
Although it is commonly agreed that all antihypertensive medications have similar efficacy, there are important differences related to safety, tolerability, patient adherence, cost effectiveness and effects on the prevention or retardation of associated disease progression. It is desirable for antihypertensives to have a long duration of action so that once-daily dosing is possible. In addition, antihypertensive medication must be able to be administered concomitantly with other drugs likely to be taken by the patients. This is particularly critical in the elderly population. Barnidipine, a novel, long-acting calcium antagonist, has met these challenges of modern pharmacotherapy. Its once-daily dosing, good tolerability and durable antihypertensive effect contribute to excellent patient adherence and make this drug a valuable addition to the antihypertensive formulary.
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Chiau‐Suong Liau (2005) conducted a review in Hypertension. Barnidipine was evaluated. Barnidipine is a novel, long-acting calcium antagonist with once-daily dosing, good tolerability, and durable antihypertensive effects for the treatment of hypertension.
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