Why the study?
Does fosinopril reduce blood pressure and what is its trough-to-peak ratio in Caucasian patients with mild to moderate hypertension?
Population
64 Caucasian patients with mild to moderate hypertension
Comparison
Fosinopril 10, 20, or 40 mg once daily for 4 weeks vs Placebo
Design
RCT, double-blind
Follow-up
4 weeks
Authors
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Supports once-daily fosinopril dosing in mild-moderate hypertension; confirms acceptable trough-to-peak ratios in this RCT.
Does fosinopril reduce blood pressure and what is its trough-to-peak ratio in Caucasian patients with mild to moderate hypertension?
Fosinopril administered once daily provides effective blood pressure reduction with acceptable trough-to-peak ratios in patients with mild to moderate hypertension.
Ford et al. (1993) studied this question.
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