Why the study?
Does fosinopril improve blood pressure reduction compared to enalapril in patients with mild to moderate essential hypertension?
Population
195 patients with mild to moderate essential hypertension, multinational.
Comparison
Fosinopril 20 mg once daily for 24 weeks, with… vs Enalapril 10 mg once daily for 24 weeks, with…
Design
RCT, randomized, parallel-group, double-blind, double-dummy technique
Follow-up
24 weeks
Authors
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Both agents achieve similar BP reductions; confirms comparable efficacy of these ACE inhibitors in mild-moderate hypertension.
Does fosinopril improve blood pressure reduction compared to enalapril in patients with mild to moderate essential hypertension?
Fosinopril and enalapril provide similar, significant reductions in blood pressure in patients with mild to moderate essential hypertension, with fosinopril being well tolerated.
Hansson et al. (1996) studied this question.
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