Population
Adult stroke-prone spontaneously hypertensive rats, normotensive Wistar-Kyoto rats, and progeny of genetic…
Comparison
Exposure of isolated helical tail artery strips… vs Comparison between different rat strains and…
Design
Preclinical
Authors
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Gene locus tied to vascular oscillations and higher BP in hypertensive rats; hypothesis-generating for human vascular genetics.
A single recessive gene locus appears to determine norepinephrine-induced oscillatory contractile activity in tail arteries of stroke-prone spontaneously hypertensive rats, which is associated with higher blood pressure.
Bruner et al. (1986) studied this question.
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