Why the study?
Does storage of blood samples at room temperature or on ice for up to 48 hours affect the measured plasma concentrations of NT-proBNP compared to immediate processing?
Population
Blood samples from 15 subjects
Comparison
Storage of blood samples for 24 h or 48 h at… vs Immediate processing
Design
Other
Follow-up
48 hours
Authors
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May permit flexible NT-proBNP sample handling up to 48 h; leaves open prospective clinical validation.
Does storage of blood samples at room temperature or on ice for up to 48 hours affect the measured plasma concentrations of NT-proBNP compared to immediate processing?
NT-proBNP extracted from plasma samples treated with EDTA and aprotinin is stable for up to 48 hours at room temperature or on ice, which is practical for routine clinical assessment of left ventricular dysfunction.
Downie et al. (1999) studied this question.
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