May 1, 1985British journal of surgery
Is tissue copper deficiency associated with aortic aneurysms?
Why the study?
Are tissue copper concentrations reduced in patients with aortic aneurysms compared to normal aortas?
Population
11 patients with aortic aneurysms and 11 fresh cadavers with normal aortas (n=22)
Design
Case-control
Authors
Discussion
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Member takes
Implication
Similar copper levels do not support deficiency in aneurysms; challenges hypothesis and leaves zinc's role open for study.
Structured PICO
Are tissue copper concentrations reduced in patients with aortic aneurysms compared to normal aortas?
P
Population
11 patients with aortic aneurysms and 11 fresh cadavers with normal aortas (n=22)
C
Comparator
11 fresh cadavers with normal aortas
O
Outcome
Levels of copper and zinc in liver and aortic wallsurrogate
This study found no evidence to support the hypothesis that aortic aneurysms are associated with reduced tissue copper concentrations.
Cite This Study
Senapati et al. (1985) studied this question.