Why the study?
Does propranolol 80 mg b.i.d. alter effective renal plasma flow and systemic circulation in patients with essential hypertension?
Population
13 patients with essential hypertension
Design
Cohort
Follow-up
8 months
Authors
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Propranolol may reduce renal plasma flow in hypertension; leaves open long-term renal effects and need for prospective trials.
Does propranolol 80 mg b.i.d. alter effective renal plasma flow and systemic circulation in patients with essential hypertension?
Propranolol treatment in essential hypertension reduces effective renal plasma flow, likely due to reduced cardiac output and altered renal hemodynamic autoregulation.
Falch et al. (1979) studied this question.
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