August 1, 1972Clinical Science

Plasma Volume and Extracellular Fluid Volume during Long-Term Treatment with Propranolol in Essential Hypertension

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Why the study?

Does propranolol affect plasma volume and extracellular fluid volume in patients with essential hypertension?

Population

10 patients with essential hypertension

Design

Case_series

Follow-up

4 months

Authors

PSP. Sederberg-OlsenUniversity of Copenhagen HIHans IbsenUppsala University

Discussion

Member takes

Implication

Should not yet change practice in essential hypertension; hypothesis-generating for propranolol's differential volume effects.

Structured PICO

Does propranolol affect plasma volume and extracellular fluid volume in patients with essential hypertension?

Population

10 patients with essential hypertension

Intervention

Propranolol 320 mg daily for 4 months

Outcome

Plasma volume and extracellular fluid volumesurrogate

Long-term treatment with propranolol in essential hypertension significantly increases extracellular fluid volume without significantly changing plasma volume.

Cite This Study

Sederberg-Olsen et al. (1972) studied this question.

synapsesocial.com/papers/6a7501bdf2cd31a1fadbf2b7 https://doi.org/10.1042/cs0430165

Topics

Hypertension management

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Plasma Volume and Extracellular Fluid Volume during Long-Term Treatment with Propranolol in Essential Hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Plasma Volume and Extracellular Fluid Volume during Long-Term Treatment with Propranolol in Essential Hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider