Why the study?
Does long-term treatment with propranolol affect glomerular filtration rate in patients with arterial hypertension?
Population
20 subjects with arterial hypertension
Comparison
Propranolol (long-term treatment) vs Withdrawal of propranolol (off-treatment state)
Design
Cohort
Authors
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Reversible GFR decline with propranolol in hypertension should not yet change practice; leaves open need for RCTs on renal outcomes.
Does long-term treatment with propranolol affect glomerular filtration rate in patients with arterial hypertension?
Long-term propranolol treatment in hypertensive patients is associated with a reversible 13% decrease in glomerular filtration rate, likely due to reduced renal blood flow.
Ibsen et al. (1973) studied this question.
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