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November 14, 2008Cardiology

The Hemodynamic and Prognostic Significance of Echo-Doppler-Proven Mitral Regurgitation in Patients with Dilated Cardiomyopathy

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Why the study?

Does the presence of mitral regurgitation detected by echocardiography predict worse hemodynamics and survival in patients with dilated cardiomyopathy?

Population

57 patients with dilated cardiomyopathy, including 21 with coronary artery disease and 36 with unproven…

Comparison

Presence of mitral regurgitation detected by… vs Absence of mitral regurgitation

Design

Cohort

Follow-up

1 year

Authors

AJAnders JunkerInterventional CardiologyPTPer ThayssenInterventional CardiologyBNBent NielsenUniversity of Cross River State

Discussion

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Overview

MR signals higher 1-year mortality risk in dilated cardiomyopathy; supports prognostic marker role but leaves open independent prediction and management impact.

Structured PICO

Does the presence of mitral regurgitation detected by echocardiography predict worse hemodynamics and survival in patients with dilated cardiomyopathy?

P
Population
57 patients with dilated cardiomyopathy (DCM), including 21 with coronary artery disease and 36 with unproven ('idiopathic') etiology.
I
Intervention
Presence of mitral regurgitation (MR) detected by color Doppler echocardiography (CDE)
C
Comparator
Absence of mitral regurgitation
O
Outcome
Survival after 1 year (analyzed as a 'worst-case situation' where cardiac transplantation equals death)hard clinical

In patients with dilated cardiomyopathy, mitral regurgitation detected by color Doppler echocardiography is a marker of reduced ventricular function, worse hemodynamics, and poor 1-year prognosis.

Cite This Study

Junker et al. (2008) studied this question.

synapsesocial.com/papers/6a724ad484cc45bb7be017fbhttps://doi.org/10.1159/000175942

Topics

Mitral valve interventionHeart failureHFrEF treatment
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Determinants of Functional Mitral Regurgitation Severity in Patients with Ischemic Cardiomyopathy versus Nonischemic Dilated Cardiomyopathy2013 · 9 citations
  2. 2The prognostic importance of left ventricular diastolic function in primary mitral regurgitation and its relation to structural changes by CMR2025 · 4 citations
  3. 3Assessing Mitral Regurgitation in Patients with Dilated Cardiomyopathy Using 3.0T Cardiac Magnetic Resonance Imaging: Correlation with Morphological and Functional Abnormalities2016
  4. 4Prognostic significance of mitral regurgitation after myocardial infarction: An echocardiography-based study2016
  5. 5Cardiopulmonary Exercise Testing and Exercise Stress Echocardiography in Degenerative Mitral Regurgitation: An Exploratory Analysis of Functional and Left Ventricular Outcomes After Surgery2026