Why the study?
Does surgical cardiac denervation reduce intrinsic heart rate in dogs?
Population
34 chronically maintained, sedated dogs
Comparison
Complete surgical cardiac denervation or… vs Normally innervated dogs
Design
Preclinical
Authors
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No immediate clinical implications; leaves open autonomic effects on intrinsic heart rate in humans.
Does surgical cardiac denervation reduce intrinsic heart rate in dogs?
Intrinsic heart rate depends on the level or nature of prevailing autonomic activity, as demonstrated by lower intrinsic rates in surgically denervated dogs.
Evans et al. (1990) studied this question.
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