Why the study?
Are AGT M235T and ACE I/D polymorphisms associated with an increased risk of essential hypertension in the Han Chinese population?
Population
19,764 individuals from 71 studies in the Han Chinese population across 23 provinces and special districts…
Comparison
Presence of AGT M235T and ACE I/D polymorphisms vs Absence of these specific genotypes (controls)
Design
Meta-analysis
Authors
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TT and DD genotypes may signal higher risk in Han Chinese; extends genetic associations but leaves clinical utility open.
Are AGT M235T and ACE I/D polymorphisms associated with an increased risk of essential hypertension in the Han Chinese population?
The AGT M235T and ACE I/D polymorphisms are significantly associated with an increased risk of essential hypertension in the Han Chinese population.
Ji et al. (2010) studied this question.
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