Why the study?
Does serial measurement of plasma FABP accurately estimate myocardial infarct size compared to CK-MB and HBDH in patients with acute myocardial infarction?
Population
49 patients with acute myocardial infarction who had been treated with thrombolytic agents within six hours…
Comparison
Serial measurement of plasma heart-type… vs Serial measurement of creatine kinase isoenzyme…
Design
Cohort
Follow-up
up to >70 hours (until completion of protein release)
Authors
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May support earlier infarct size estimation in AMI; hypothesis-generating and should not yet change practice.
Does serial measurement of plasma FABP accurately estimate myocardial infarct size compared to CK-MB and HBDH in patients with acute myocardial infarction?
Plasma FABP is a useful and earlier biochemical marker for estimating myocardial infarct size compared to traditional enzymes like CK-MB.
Glatz et al. (1994) studied this question.
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