Why the study?
Does metoprolol 150-450 mg daily provide effective antihypertensive effects and tolerability in patients with essential hypertension?
Does metoprolol 150-450 mg daily provide effective antihypertensive effects and tolerability in patients with essential hypertension?
Metoprolol at 150-450 mg daily is an effective and well-tolerated long-term treatment for essential hypertension.
Should not yet change practice in essential hypertension; hypothesis-generating observational support for metoprolol tolerability.
One hundred and forty-seven patients with essential hypertension participated in this multicentre study. The results indicate that metoprolol in a dosage of 150-450 mg daily is an effective and well tolerated therapy both in patients previously untreated and in patients unsatisfactorily treated with other antihypertensive agents.
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S. Rosengård (1977) studied this question.
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