Key result
Metoprolol effectively lowers blood pressure and is well tolerated in hypertensive patients.
Why the study?
Does metoprolol reduce blood pressure in hypertensive patients?
Does metoprolol reduce blood pressure in hypertensive patients?
Metoprolol is an effective and well-tolerated treatment for reducing blood pressure in hypertensive patients at doses of 100 to 400 mg daily.
Hypothesis-generating for metoprolol dosing in hypertension; larger RCTs needed before practice change.
An open study of the effectiveness of metoprolol in reducing the blood pressures of 13 hypertensive patients was conducted. It was found that metoprolol reduced the patients' blood pressure satisfactorily, and is well tolerated within the dose range of 100 mg to 400 mg daily.
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McNeil et al. (1978) studied this question. Metoprolol effectively reduced blood pressure and was well tolerated at daily doses of 100 to 400 mg in hypertensive patients.
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