Why the study?
Does atenolol compared to pindolol alter fetal hemodynamics in women with pregnancy-induced hypertension?
Population
29 women with pregnancy-induced hypertension in the third trimester
Comparison
Atenolol vs Pindolol
Design
RCT, randomised, double blind double dummy
Authors
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Atenolol but not pindolol impairs fetal hemodynamics in pregnancy-induced hypertension; challenges beta-1 selective blocker safety in this setting.
Does atenolol compared to pindolol alter fetal hemodynamics in women with pregnancy-induced hypertension?
In women with pregnancy-induced hypertension, atenolol significantly alters fetal hemodynamics and reduces placental weight compared to pindolol, raising concerns about potential negative fetal consequences of beta-1 blockade.
Montán et al. (1992) studied this question.
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