Why the study?
Does smoking cessation reverse endothelial dysfunction in human hand veins of heavy smokers?
Population
34 subjects (18 heavy smokers and 16 nonsmoker controls)
Comparison
Acute smoking cessation and L-arginine coinfusion vs Nonsmoker controls and baseline smoking status
Design
Cohort
Follow-up
24 hours
Authors
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Supports rapid reversibility of smoking-induced venous endothelial dysfunction; leaves open translation to arteries and events.
Does smoking cessation reverse endothelial dysfunction in human hand veins of heavy smokers?
Endothelial dysfunction in the veins of heavy smokers is rapidly reversible within 24 hours of smoking cessation.
Moreno et al. (1998) studied this question.
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