Why the study?
What is the intraindividual variability of fibrinogen levels and how does it affect the accuracy of cardiovascular risk stratification?
What is the intraindividual variability of fibrinogen levels and how does it affect the accuracy of cardiovascular risk stratification?
High intraindividual variability in fibrinogen levels demonstrates that a single measurement is insufficient for accurate cardiovascular risk stratification, requiring multiple measurements to minimize misclassification.
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Single fibrinogen measures may misclassify cardiovascular risk; leaves open whether repeated sampling improves stratification accuracy in outcome studies.
Rosenson et al. (1994) studied this question.
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