Why the study?
Does captopril lower blood pressure in anephric patients?
Population
5 anephric patients with extremely low plasma renin activities
Design
Case_series
Authors
Loading...
May not lower BP in anephric patients; leaves open whether intact renal renin-angiotensin system is required for efficacy.
Does captopril lower blood pressure in anephric patients?
The blood-pressure lowering effect of captopril depends on an active renal renin-angiotensin system, as it fails to lower blood pressure in anephric patients.
Leslie et al. (1980) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: