Why the study?
Does alprenolol compared to propranolol reduce blood pressure and heart rate in patients with essential hypertension?
Population
16 patients with essential hypertension
Comparison
Alprenolol 400 mg daily vs Propranolol 160 mg daily (crossover design)
Design
RCT, double-blind
Follow-up
three months
Authors
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Alprenolol matches propranolol for BP and HR reduction in essential hypertension; confirms equipotent beta-blocker efficacy in this RCT.
Does alprenolol compared to propranolol reduce blood pressure and heart rate in patients with essential hypertension?
Alprenolol and propranolol demonstrate equipotent antihypertensive efficacy in patients with essential hypertension.
Somer et al. (1974) studied this question.
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