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April 11, 1957New England Journal of Medicine

Severe Aortic Regurgitation in Young People

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Why the study?

Does the plastic valve of Hufnagel provide effective palliation in young patients with severe rheumatic aortic regurgitation when medical measures fail?

Population

Young patients with rheumatic heart disease whose principal lesion is aortic regurgitation of an extreme…

Design

Case_series

Authors

EBEdward F. BlandAustralian National UniversityEWEdwin O. WheelerHarvard University

Discussion

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Implication

Case observations in refractory rheumatic AR leave open any palliative role for the Hufnagel valve; prospective evaluation required before consideration.

Structured PICO

Does the plastic valve of Hufnagel provide effective palliation in young patients with severe rheumatic aortic regurgitation when medical measures fail?

P
Population
Young patients with rheumatic heart disease whose principal lesion is aortic regurgitation of an extreme degree
I
Intervention
Plastic valve of Hufnagel as a palliative maneuver when medical measures fail

This early report describes the clinical features of severe rheumatic aortic regurgitation in young patients and initial experience with the Hufnagel plastic valve as a palliative treatment.

Cite This Study

Bland et al. (1957) studied this question.

synapsesocial.com/papers/6a7406933052772b87ff79c8https://doi.org/10.1056/nejm195704112561501

Topics

Valvular heart diseaseCongenital heart disease adults
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Contemporary Overview of Aortic Regurgitation in Young Individuals: Insights From Real‐Life Evidence2026 · 1 citations
  2. 2Valve replacement for rheumatic aortic incompetence in adolescents.1978 · 2 citations
  3. 3Acute Severe Aortic Regurgitation1977 · 109 citations
  4. 4Ventricular septal defect and aortic regurgitation1969 · 25 citations
  5. 5Severe aortic regurgitation and pulmonary hypertension in an 18-year-old patient after balloon aortic valvuloplasty (RCD code: IV-5.A2)2016