Population
Sewage and polluted river samples
Comparison
Viral concentration by centrifugation, elution… vs Tissue culture analysis
Design
Other
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Supports nested PCR for sensitive viral monitoring in water; leaves open standardization for regulatory use.
A nested PCR method provides higher sensitivity than tissue culture for detecting adenoviruses and enteroviruses in environmental water samples.
A 1995 study studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: