Why the study?
Does captopril plus diuretics improve long-term survival and clinical outcomes compared to digoxin plus diuretics in patients with mild to moderate heart failure?
Does captopril plus diuretics improve long-term survival and clinical outcomes compared to digoxin plus diuretics in patients with mild to moderate heart failure?
In patients with mild to moderate heart failure, captopril showed a trend toward improved long-term survival compared to digoxin, though the trial was terminated prematurely.
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Trend toward lower mortality with captopril versus digoxin in mild-moderate HF; leaves open survival benefit of ACE inhibitors over digoxin.
Cosín‐Aguilar et al. (1999) studied this question.
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