What question did this study set out to answer?

To evaluate cardiovascular and haemodynamic changes in women with mild hypertension during pregnancy compared to normotensive controls.

March 1, 1979BJOG An International Journal of Obstetrics & Gynaecology

Haemodynamics of Mild Hypertension in Pregnancy

View Full Paper

Ask AI

Bookmark

Why the study?

How do haemodynamic parameters differ between mildly hypertensive and normotensive women during pregnancy?

Population

48 pregnant women (25 mildly hypertensive and 23 normotensive)

Comparison

Mild hypertension (exposure) vs Normotensive pregnancy

Design

Cohort

Follow-up

Serial measurements during pregnancy

Authors

YLY.L. LimTan Tock Seng Hospital WWW.A.W. WaltersHunter Medical Research Institute

Discussion

Member takes

Implication

Mild gestational hypertension linked to hyperkinetic hemodynamics; leaves open sympathetic role and need for outcome trials before practice change.

Key Points

To evaluate cardiovascular and haemodynamic changes in women with mild hypertension during pregnancy compared to normotensive controls.
Conducted 163 serial haemodynamic evaluations across 23 normotensive and 25 mildly hypertensive pregnant women in the left lateral resting position.
Heart rate, cardiac output, stroke volume, left ventricular work index, total peripheral vascular resistance, and haematocrit were significantly higher in hypertensive pregnant women than in normotensive controls.
Plasma volume per unit of body weight was significantly lower in the mildly hypertensive group compared to the normotensive group.

Structured PICO

How do haemodynamic parameters differ between mildly hypertensive and normotensive women during pregnancy?

Population

48 pregnant women (25 mildly hypertensive and 23 normotensive)

Intervention

Mild hypertension (exposure)

Comparator

Normotensive pregnancy

Outcome

Haemodynamic parameters (heart rate, cardiac output, stroke volume, left ventricular work index, total peripheral vascular resistance, haematocrit, and plasma volume per unit body weight)surrogate

Mild hypertension in pregnancy is characterized by a hyperkinetic circulatory state, which may be driven by sympathetic adrenergic hyperactivity.

Cite This Study

Lim et al. (1979) studied this question.

synapsesocial.com/papers/6a74719780fadadbba090dc1 https://doi.org/10.1111/j.1471-0528.1979.tb10593.x

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Implication

Mild gestational hypertension linked to hyperkinetic hemodynamics; leaves open sympathetic role and need for outcome trials before practice change.

Haemodynamics of Mild Hypertension in Pregnancy

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Haemodynamics of Mild Hypertension in Pregnancy

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider