Why the study?
Do PDE4D gene polymorphisms increase the risk of ischemic stroke and asymptomatic carotid atherosclerosis in a European population?
Population
737 consecutive white patients with stroke and 933 white community controls free of symptomatic…
Comparison
19 single nucleotide polymorphisms and 1… vs Healthy community controls and subjects without…
Design
Case-control
Authors
Loading...
PDE4D variants are not major risk factors for ischemic stroke or carotid atherosclerosis; challenges earlier broad associations and leaves subtype links open.
Do PDE4D gene polymorphisms increase the risk of ischemic stroke and asymptomatic carotid atherosclerosis in a European population?
The PDE4D gene is not a major risk factor for ischemic stroke overall or early atherosclerosis in this European population, failing to replicate earlier broad associations.
Bevan et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: