May 1, 1990AJP Heart and Circulatory Physiology

Acute open-chest complete heart block by transeptal electrocoagulation

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Population

15 male mongrel dogs, anesthetized with alpha-chloralose, intubated, and ventilated

Design

Preclinical

Follow-up

3-4 hours

Authors

JTJames TonkinRoyal Brompton Hospital LDLouis G. D’AlecyUniversity of Michigan

Discussion

Member takes

Implication

May facilitate preclinical complete heart block models; leaves open translation to human use pending further validation.

Structured PICO

Population

15 male mongrel dogs, anesthetized with alpha-chloralose, intubated, and ventilated

Intervention

Transeptal electrocoagulation using an electrocautery pinch-clamp device applied to the atrial septum for 10-15 seconds to destroy the atrioventricular node and His bundle

Outcome

Production of stable complete heart block (CHB) lasting at least 3-4 hours

A novel transeptal electrocoagulation pinch-clamp device reliably produces complete heart block in open-chest dog models without causing structural damage.

Cite This Study

Tonkin et al. (1990) studied this question.

synapsesocial.com/papers/6a74f2f0756843cacbb1de31 https://doi.org/10.1152/ajpheart.1990.258.5.h1599

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Acute open-chest complete heart block by transeptal electrocoagulation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Acute open-chest complete heart block by transeptal electrocoagulation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider