Why the study?
Is insulin action associated with endothelial function in male patients with essential hypertension or type 2 diabetes?
Population
Male patients with essential hypertension or type 2 diabetes along with healthy control subjects matched for…
Comparison
Measurement of whole-body insulin sensitivity by… vs Healthy control subjects matched for age, body…
Design
Cross-sectional
Follow-up
3 days
Authors
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No practice change from cross-sectional associations; leaves open whether targeting insulin sensitivity improves endothelial function in hypertension or diabetes.
Is insulin action associated with endothelial function in male patients with essential hypertension or type 2 diabetes?
The study demonstrates a functional coupling between metabolic and vascular insulin action and basal endothelial nitric oxide production in humans.
Cleland et al. (2000) studied this question.
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