Why the study?
Does superoxide dismutase improve contractile performance and preserve myocardial structure following ischemia and reperfusion in an isolated rabbit septal model?
Population
Isolated perfused rabbit interventricular septal preparation
Comparison
Superoxide dismutase 10 or 20 micrograms/ml… vs Nontreated septa
Design
Preclinical
Follow-up
60 minutes of reflow
Authors
Loading...
SOD improves postischemic recovery in isolated rabbit septa; hypothesis-generating for radical scavenging in reperfusion injury, requiring in vivo and clinical validation.
Does superoxide dismutase improve contractile performance and preserve myocardial structure following ischemia and reperfusion in an isolated rabbit septal model?
Superoxide dismutase preserves myocardial function and structure following ischemia and reperfusion in an ex vivo rabbit model, supporting the role of oxygen-derived free radicals in reperfusion injury.
Karen P. Burton (1985) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: