Population
Human forearm flexor muscle data measured byP-NMR spectroscopy used for a network model of ATP free energy…
Design
Preclinical
Authors
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Informs dynamic models of skeletal muscle energetics; leaves open cardiac translation and human studies.
In skeletal muscle, ATP flux control shifts from ATP demand (actomyosin ATPase) to ATP supply (mitochondria) as contraction frequency increases, demonstrating inherent homeostasis.
Jeneson et al. (2000) studied this question.
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