Why the study?
Does a high-sensitivity cardiac troponin I assay accurately detect acute rejection in cardiac transplant recipients?
Does a high-sensitivity cardiac troponin I assay accurately detect acute rejection in cardiac transplant recipients?
A high-sensitivity cTnI assay demonstrates a 99% negative predictive value for acute rejection, suggesting it could be a useful noninvasive tool to rule out rejection and reduce the need for surveillance biopsies in heart transplant recipients.
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May support hs-cTnI to rule out rejection in transplant recipients; leaves open whether it can safely reduce surveillance biopsies.
Patel et al. (2014) studied this question.
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