Population
Human cells (in vitro model for hepatitis B virus P gene expression)
Design
Preclinical
Authors
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No immediate implications for HBV care; hypothesis-generating for P gene translation mechanisms requiring in vivo validation.
This study demonstrates that hepatitis B virus P gene expression in human cells involves internal entry of ribosomes and leaky scanning, explaining the synthesis of two forms of reverse transcriptase.
Jean‐Jean et al. (1989) studied this question.
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