The bovine beta(3) subunit, specifically its C-terminal one-third ectodomain, is responsible for the high-efficiency utilization of the integrin alpha(v)beta(3) receptor by Foot-and-mouth disease virus.
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Highlights species-specific integrin requirements for FMDV; leaves open whether beta(3) targeting informs tropism or control strategies.
Neff et al. (2000) studied this question.
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