Why the study?
Does coating defibrillation leads with ePTFE or backfilling with medical adhesive improve extraction outcomes and reduce tissue trauma in a sheep model?
Population
24 sheep implanted with a coronary sinus shocking lead in the distal portion of the great cardiac vein
Comparison
Shocking coils backfilled with medical adhesive… vs Unmodified shocking coils (control)
Design
Preclinical
Follow-up
up to 14 months
Authors
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Does not support coated leads in practice; leaves open translation of reduced fibrosis to human extraction safety.
Does coating defibrillation leads with ePTFE or backfilling with medical adhesive improve extraction outcomes and reduce tissue trauma in a sheep model?
Coating defibrillation shocking coils with ePTFE or backfilling with medical adhesive reduces tissue ingrowth and facilitates transvenous lead removal with less tissue trauma in an animal model.
Wilkoff et al. (2005) studied this question.
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