Why the study?
Patients with ischemic heart failure on guideline-directed medical therapy still struggle with poor cardiac function and high readmission rates, making enhancement of cardiac function a critical challenge.
Does Qishen Yiqi dripping pills improve ejection fraction classification in patients with ischaemic heart failure on guideline-directed medical therapy?
Population
1,225 patients with IHF (HFrEF and HFmrEF) from 84 centres
Comparison
Additional QSYQ with GDMT vs GDMT alone
Design
Multicentre prospective cohort study with propensity score matching
Follow-up
90 days
Authors
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May support adjunctive Qishen Yiqi in IHF on GDMT; hypothesis-generating and requires RCT confirmation before practice change.
Does Qishen Yiqi dripping pills improve ejection fraction classification in patients with ischaemic heart failure on guideline-directed medical therapy?
The addition of Qishen Yiqi dripping pills to guideline-directed medical therapy significantly improves ejection fraction classification and reduces adverse clinical events in patients with ischemic heart failure.
Zhou et al. (2025) studied this question.
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