Why the study?
Does lysine enhancement and increased glutaraldehyde concentration reduce calcification of bioprosthetic heart-valve materials in a subcutaneous rat model?
Does lysine enhancement and increased glutaraldehyde concentration reduce calcification of bioprosthetic heart-valve materials in a subcutaneous rat model?
Lysine incorporation and increased glutaraldehyde concentration significantly decrease the calcification potential of bioprosthetic heart valve tissues in a preclinical model.
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May limit bioprosthetic valve calcification in preclinical models; leaves open clinical translation pending human trials.
Bezuidenhout et al. (2009) studied this question.
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