Why the study?
Does long-term dexamethasone correct hypertension and restore aldosterone responsiveness in patients with glucocorticoid-suppressible hyperaldosteronism?
Population
2 males with glucocorticoid-suppressible hyperaldosteronism, hypertension, and hypokalaemia
Design
Case_series
Follow-up
more than a year
Authors
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May support physiological-dose dexamethasone for sustained control in glucocorticoid-suppressible hyperaldosteronism; leaves open confirmation in controlled trials.
Does long-term dexamethasone correct hypertension and restore aldosterone responsiveness in patients with glucocorticoid-suppressible hyperaldosteronism?
Long-term physiological dexamethasone therapy corrects hypertension and restores normal renin-angiotensin-aldosterone axis regulation in patients with glucocorticoid-suppressible hyperaldosteronism.
Woodland et al. (1985) studied this question.
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