Key result
Treatment with the UKALL 14 chemotherapy protocol resulted in complete resolution of heart failure symptoms and normalization of cardiac function in a patient with acute lymphoblastic leukemia.
Population
A 29-year-old male with no past medical history presenting with ALL and heart failure
Design
Case report
Authors
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ALL infiltration may cause reversible cardiomyopathy; single case leaves open need for hematologic evaluation in unexplained heart failure.
Case Report (n=1)
Acute lymphoblastic leukemia can rarely present as acute decompensated heart failure due to infiltrative cardiomyopathy, which can be completely reversed with appropriate chemotherapy.
Abdelghani et al. (2023) conducted a case report in Acute lymphoblastic leukemia with acute decompensated heart failure (n=1). UKALL 14 chemotherapy protocol was evaluated on Resolution of heart failure symptoms and normalization of cardiac function. Treatment with the UKALL 14 chemotherapy protocol resulted in complete resolution of heart failure symptoms and normalization of cardiac function in a patient with acute lymphoblastic leukemia.
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